The impact of soy consumption on fertility has been a subject of ongoing debate. Soy contains phytoestrogens such as isoflavones, which have a chemical structure similar to estrogen and can bind to estrogen receptors in the body, influencing fertility outcomes. Animal studies have demonstrated that high soy or isoflavone levels may disrupt the hormonal balance and negatively affect fertility. However, human studies have reported conflicting results, with some indicating no association and others showing a strong association between soy consumption and infertility. Variability in study designs, populations, lack of randomized controlled trials, inadequate understanding of the underlying mechanisms, and dietary intake assessment methods contribute to inconclusive findings. While some studies have suggested potential concerns about soy and fertility, the overall evidence remains inconclusive, and further research is required to elucidate this complex relationship. Personalized advice from healthcare professionals remains optimal for individuals with fertility issues.

ABSTRACT Background: Data backup is an important component of data protection and management. It is especially imperative to back up large-scale data to guard against losses due to hardware failure, unauthorized access, software/system malfunction, and unintended deletion. However, businesses and organizations suffer from the financial investment required for data backup and recovery systems. Health-care systems suffer from data breaches and hacking incidents, which increase annually. Therefore, a cost-effective and highly secure backup approach is necessary. Methods: Seven different backup scripts were written in bash within Linux, and Crontab was used as the core chronological scheduler to execute the backup scripts on specific dates and times. These bash scripts, together with Crontab as their scheduler, were used to implement automated incremental backups on a Unix/Linux-based system. Results: ChronoBak is a collection of bash scripts that are compiled and executed through Crontab, which is a standard Unix/Linux function used to schedule hourly, daily, weekly, and monthly maintenance routines using Linux scripts. This strategy enabled us to implement cost-effective incremental backups within any time range. Conclusion: We developed ChronoBak software, which executes an automated incremental backup that is scheduled efficiently and systematically using standard and hidden directories, thereby providing an additional layer of security against cyber threats and system malfunctions.

Background: The global search for a safe, irreversible cure after lethal radiation exposure and cancer has not been successful since World War II. Nuclear warfare cannot be recreated in a laboratory. Simulation experiments require highly classified, expensive, and approved infrastructure. Chemotherapy and radiotherapy affect both healthy and damaged cells and often lead to cancer recurrence. A lethal dose of ionizing radiation (IR) is devastating because of instant, massive, and diffuse DNA breaks, chromosomal aberrations, tissue oxidation, and the cascading generation of free radicals, and it can cause cancer. People exposed to a nuclear attack directly cannot be cured. Methods: A formulation comprising aqueous extracts of leaves of Indian bael (Aegle marmelos) and Oxalis corniculate, roots of ginseng (Panax ginseng), custard apple (Annona squamosa) or sitaphal cotyledons, methi (Fenugreek) seeds, and lytic Newcastle disease virus (nonhuman) was used. A few doses of the formulation were injected intraperitoneally into lethally gamma-irradiated mice; mice were also injected with Ehrlich ascites carcinoma cells. Breast and cervical cancer cells were treated with this formulation in vitro. Results: We have developed a solution to the lasting problem. The formulation induced apoptosis in IR-damaged cancer cells by the developed formulation in vivo and in vitro, with no subsequent regrowth. No adverse effects were observed. The control ‘DF1’ Fibroblast cells did not exhibit any change after the drug administration. A possible explanation is the loss of defense responses in damaged cells, allowing the multiplication of the killer virus. Thus, people with cancer and those who escape the direct impacts of nuclear accidents may be saved. The lyophilized components can be stored at room temperature under field conditions. Conclusion: Successful treatment with herbs and virotherapy (a nanomedicine) can be delivered as tablets (a stable formulation) to remote areas, which may be a permanent solution to the prolonged search for the treatment of radiation exposure.